Self Care - Spinal Compression Fracture

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Outpatient Therapy

Julie Kramer, SPT

Title: Quality-of-Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO)
Purpose: To assess the quality of life and changes over treatment among patients with established vertebral osteoporosis.1
Description: QUALEFFO contains a series of questions that cover five domains of quality of life. These include pain, physical function (ADLs, mobility, tasks around the house), social function, general health perception, and mental function (mood).1,2 The different domains can be scored individually or collectively depending on the needs of the clinician administering the questionnaire.
ICF Domain: Activity, participation
Time to administer: 20-30 minutes
Number of items: 411
Equipment required: None
Training required: None
Cost: Free
Population: Osteoporosis, vertebral fractures1,2
Minimal Detectable Change (MDC): Not established
Minimal Clinically Important Difference (MDIC): Not established
Cut-off scores: Not established
Criterion validity: Not established
Construct validity: Good discriminate validity; questions correlate best within their own domain than in other domains.2
Floor/Ceiling effects: By Domain Category2

  • Pain: Floor = 0; Ceiling = 6.7%
  • Physical function: Floor = 0; Ceiling = 0.6%
  • Social function: Floor = 1.9%; Ceiling = 5.7%
  • General health perception: Floor = 3.1%; Ceiling = 1.2%
  • Mental function: Floor = 0.6%; Ceiling = 0.6%

Considerations: None


1. Tosteson ANA, Hammond CS. Quality-of-life assessment in osteoporosis: Health-status and preference-based measures. Pharmacoeconomics. 2002;20(5):289-303.

2. Lips P, Cooper C, Agnusdei D, et al. Quality of life in patients with vertebral fractures: Validation of the quality of life questionnaire of the European foundation for osteoporosis (QUALEFFO). Osteoporos Int. 1999;10(2):150-160. doi: 10.1007/s001980050210.

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